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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of hsa-miR-146a
ncRNA name hsa-miR-146a
ncRNA Category miRNA
Disease name Graves disease
Species Homo sapiens
Tissues/Cell_line peripheral blood mononuclear cells (PBMCs)
Methods flow cytometry, microarray, qPCR, Western blot
Expression pattern down-regulated
Functional description There were 23 up-regulated and 14 down-regulated miRNAs between three GD sample pools and control sample pools. miR-519e–5p, miR-30a–5p, miR-19b, miR-146a and miR-155 were validated by LNA qPCR in another 30 patients with iuGD and 30 controls.
PubMed ID 25233152
Year 2014
Title Integrative analysis of mRNA and miRNA array data reveals the suppression of retinoic acid pathway in regulatory T cells of Graves' disease.
Drug-related ncRNA NO

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